Leucovorin & Autism: What Families Need to Know
Leucovorin & Autism
Leucovorin (prescription-strength folinic acid) is a form of folate (vitamin B9) that can play an important role in supporting brain health, especially for individuals diagnosed with autism who have autoantibodies preventing folate from reaching the brain.
This page brings together trusted information, expert insight, and family resources to help you learn more.
The Science: Cerebral Folate Deficiency
Learn about Cerebral Folate Deficiency (CFD), a condition where there is a normal amount of folate in the blood but not enough folate reaching the brain. This can impact communication, behavior, and development. Discover how Leucovorin can help overcome this barrier and support healthy brain function.
Listen: Expert Interview
Hear directly from Dr. Richard Frye, a leading researcher and clinician, as he explains:
What is Leucovorin
How it may help individuals with autism
What families should know before starting treatment
Learn In Person
Join us at the TACA National Autism Conference this October 10 –12 in Costa Mesa, CA to hear experts discuss Leucovorin, folate pathways, and other emerging treatments. Can’t attend in person? No problem, you can purchase all of the presentations through our Recorded Access ticket and get educated from the comfort of your home!
Get Support with TACA - Hope & Help for Autism Facebook Group
You don’t have to navigate this alone. Connect with other parents in the TACA - Hope & Help for Autism Facebook group, where trained staff and experienced families provide guidance and encouragement.
Attend Virtual Meetings
Participate in upcoming Zoom meetings (event details coming soon) to learn more, ask questions, and connect with other families exploring Leucovorin.
Parent Resources
- TACA Autism Workbook – Practical tools, checklists, and step-by-step guides for families.
- Treatment & Therapy Articles – Explore evidence-based resources to better understand autism interventions.
Healthy Babies: Prevention Matters
Planning for pregnancy or already expecting? Learn about strategies for a healthy pregnancy, including the role of folate and nutrition before and during pregnancy.
Support Our Efforts
- Your gift helps TACA provide families with access to education, resources, and hope.